▍Backgound

FGF-4 (fibroblast growth factor-4), also known as FGF-K or K-FGF (Kaposi’s sarcoma-associated FGF), is a 25 kDa secreted, heparin-binding member of the FGF family. The human FGF-4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF-4 (aa 71-206) shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF-4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2c, 3c and 4, is spatially and temporally regulated during embryonic development. Its expression in the mouse trophoblast inner cell mass promotes expression of FGF R2, and is required for maintenance of the trophectoderm and primitive endoderm.

▍Source

Recombinant Human FGF-4 is expressed from Escherichia coli. It contains AA Ser 71 - Leu 206. Predicted molecular mass 19.6 kDa. This protein carries a polyhistidine tag at the N-terminus.

Recombinant Human FGF-4 is expressed from Escherichia coli

▍Endotoxin

Less than 1.0 EU per μg by the LAL method.

▍AA Sequence

SGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPG

MFIALSKNGKTKKGNRVSPTMKVTHFLPRL

▍Purity

Purity >95% as determined by SDS-PAGE.

▍Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.

▍Reconstitution

Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.

▍Storage

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

▍SDS-PAGE

Human FGF-4, His Tag on SDS-PAGE under reducing (R) condition

Human FGF-4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

廈門逸漠生物科技有限公司(Xiamen Immocell Biotechnology Co.,Ltd.)坐落于廈門國(guó)家留學(xué)創(chuàng)業(yè)園(翔安)產(chǎn)業(yè)園，是一家專注于細(xì)胞生物學(xué)領(lǐng)域新產(chǎn)品、新技術(shù)開發(fā)的高新技術(shù)企業(yè)。
公司擁有一支具有深厚造詣和豐富經(jīng)驗(yàn)的高端技術(shù)人才，建設(shè)了高規(guī)格的研發(fā)實(shí)驗(yàn)室與生產(chǎn)車間，建立了規(guī)范的研發(fā)、生產(chǎn)、銷售、客服管理體系。
公司與國(guó)內(nèi)外多家醫(yī)院、高等院校、科研院所、生物醫(yī)藥公司建立了良好的合作關(guān)系，贏得了良好的市場(chǎng)聲譽(yù)和廣泛的客戶認(rèn)可，將努力成為生命科學(xué)界可靠的合作伙伴和堅(jiān)強(qiáng)的技術(shù)后盾。
企業(yè)文化我們的使命：
深耕細(xì)胞技術(shù)，共筑人類健康從細(xì)胞技術(shù)著手，深入地、多維度地進(jìn)行探索與積累,發(fā)展新產(chǎn)品與、新技術(shù)服務(wù)于生命科技探索以及人類疾病診療、人類健康發(fā)展事業(yè)。
我們的愿景：
成為生命科學(xué)領(lǐng)域被認(rèn)可與喜歡的公司我們旨在構(gòu)建細(xì)胞資源與應(yīng)用中心。我們追求為客戶提供靠譜的產(chǎn)品與技術(shù)，讓他們能夠省心省力的專注于自己的科研工作。我們的愿景是讓客戶獲得成功的同時(shí)。成為他們的心中認(rèn)可與喜歡的公司。
我們的經(jīng)營(yíng)理念：
1.精益求精、開拓創(chuàng)新把成熟的產(chǎn)品做到非凡，把創(chuàng)新的產(chǎn)品做到超乎想象。
2.專業(yè)高效、合作共贏專業(yè)就是力量，專業(yè)才能高效;合作就會(huì)發(fā)展、合作才能共贏。我們秉持這種理念，以我們專業(yè)的產(chǎn)品和服務(wù)，與廣大合作伙伴共同應(yīng)對(duì)挑戰(zhàn),共同發(fā)展進(jìn)步。
我們的價(jià)值觀：
1.勇于探索逸漠的精髓基于勇敢地探索，于逆境中的自我激勵(lì)、奮然而起，于順境中自我挑戰(zhàn)、自我超越。逸漠人選擇創(chuàng)造更多的價(jià)值，選擇擁有精彩的人生。
2.團(tuán)結(jié)奮進(jìn)面對(duì)神奇的世界、美好的未來，我們心懷敬畏與謙卑。我們改變自己,適應(yīng)時(shí)代，我們團(tuán)結(jié)一致、凝聚力量，努力學(xué)習(xí)、不斷進(jìn)步，一起展現(xiàn)我們的創(chuàng)造力與影響力。
3.守護(hù)誠(chéng)信逸漠發(fā)展的過程就是不斷被別人認(rèn)可的過程。我們忠誠(chéng)于自己的事業(yè)，守信于他人的事務(wù)，這是我們的寶貴的財(cái)富、強(qiáng)大的基石。我們建立誠(chéng)信、珍惜誠(chéng)信，可以讓我們更加專注于處理自己的事情，也讓事情處理起來更加簡(jiǎn)單、高效。
4.關(guān)愛生命尊重與關(guān)愛生命，是我們職責(zé)，也是我們的發(fā)展動(dòng)力。我們守護(hù)自己與家人，快樂工作，享受生活;我們珍視生存的世界，崇尚和諧、友善的人際關(guān)系;熱愛優(yōu)美、多彩的人居環(huán)境。