▍Backgound

Human Interleukin-13 (IL-13) is expressed by the IL13 gene located on the chromosome 5 and secreted by many cell types, especially T helper type 2 (Th2) cells. The high solution from of IL-13 reported to be a monomer with two internal disulfide bonds that contribute to a bundled four α-helix configuration. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Human, mouse and rat IL-3 share low homology, but have cross species activity.

▍Source

Recombinant Human IL-13 is expressed from Escherichia coli. It contains AA Gly 21 - Asn 132. Predicted molecular mass 15.2 kDa. This protein carries a polyhistidine tag at the N-terminus.

Recombinant Human IL-13 is expressed from Escherichia coli

▍Endotoxin

Less than 1.0 EU per μg by the LAL method.

▍AA Sequence

GPVPPSTALR ELIEELVNIT QNQKAPLCNG SMVWSINLTA GMYCAALESL INVSGCSAIE KTQRMLSGFC PHKVSAGQFS SLHVRDTKIE VAQFVKDLLL HLKKLFREGR FN

▍Purity

Purity >90% as determined by SDS-PAGE.

▍Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.

▍Reconstitution

Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.

▍Storage

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

▍SDS-PAGE

Human IL-13, His Tag on SDS-PAGE under reducing (R) condition

Human IL-13, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

廈門(mén)逸漠生物科技有限公司(Xiamen Immocell Biotechnology Co.,Ltd.)坐落于廈門(mén)國(guó)家留學(xué)創(chuàng)業(yè)園(翔安)產(chǎn)業(yè)園，是一家專(zhuān)注于細(xì)胞生物學(xué)領(lǐng)域新產(chǎn)品、新技術(shù)開(kāi)發(fā)的高新技術(shù)企業(yè)。
公司擁有一支具有深厚造詣和豐富經(jīng)驗(yàn)的高端技術(shù)人才，建設(shè)了高規(guī)格的研發(fā)實(shí)驗(yàn)室與生產(chǎn)車(chē)間，建立了規(guī)范的研發(fā)、生產(chǎn)、銷(xiāo)售、客服管理體系。
公司與國(guó)內(nèi)外多家醫(yī)院、高等院校、科研院所、生物醫(yī)藥公司建立了良好的合作關(guān)系，贏得了良好的市場(chǎng)聲譽(yù)和廣泛的客戶認(rèn)可，將努力成為生命科學(xué)界可靠的合作伙伴和堅(jiān)強(qiáng)的技術(shù)后盾。
企業(yè)文化我們的使命：
深耕細(xì)胞技術(shù)，共筑人類(lèi)健康從細(xì)胞技術(shù)著手，深入地、多維度地進(jìn)行探索與積累,發(fā)展新產(chǎn)品與、新技術(shù)服務(wù)于生命科技探索以及人類(lèi)疾病診療、人類(lèi)健康發(fā)展事業(yè)。
我們的愿景：
成為生命科學(xué)領(lǐng)域被認(rèn)可與喜歡的公司我們旨在構(gòu)建細(xì)胞資源與應(yīng)用中心。我們追求為客戶提供靠譜的產(chǎn)品與技術(shù)，讓他們能夠省心省力的專(zhuān)注于自己的科研工作。我們的愿景是讓客戶獲得成功的同時(shí)。成為他們的心中認(rèn)可與喜歡的公司。
我們的經(jīng)營(yíng)理念：
1.精益求精、開(kāi)拓創(chuàng)新把成熟的產(chǎn)品做到非凡，把創(chuàng)新的產(chǎn)品做到超乎想象。
2.專(zhuān)業(yè)高效、合作共贏專(zhuān)業(yè)就是力量，專(zhuān)業(yè)才能高效;合作就會(huì)發(fā)展、合作才能共贏。我們秉持這種理念，以我們專(zhuān)業(yè)的產(chǎn)品和服務(wù)，與廣大合作伙伴共同應(yīng)對(duì)挑戰(zhàn),共同發(fā)展進(jìn)步。
我們的價(jià)值觀：
1.勇于探索逸漠的精髓基于勇敢地探索，于逆境中的自我激勵(lì)、奮然而起，于順境中自我挑戰(zhàn)、自我超越。逸漠人選擇創(chuàng)造更多的價(jià)值，選擇擁有精彩的人生。
2.團(tuán)結(jié)奮進(jìn)面對(duì)神奇的世界、美好的未來(lái)，我們心懷敬畏與謙卑。我們改變自己,適應(yīng)時(shí)代，我們團(tuán)結(jié)一致、凝聚力量，努力學(xué)習(xí)、不斷進(jìn)步，一起展現(xiàn)我們的創(chuàng)造力與影響力。
3.守護(hù)誠(chéng)信逸漠發(fā)展的過(guò)程就是不斷被別人認(rèn)可的過(guò)程。我們忠誠(chéng)于自己的事業(yè)，守信于他人的事務(wù)，這是我們的寶貴的財(cái)富、強(qiáng)大的基石。我們建立誠(chéng)信、珍惜誠(chéng)信，可以讓我們更加專(zhuān)注于處理自己的事情，也讓事情處理起來(lái)更加簡(jiǎn)單、高效。
4.關(guān)愛(ài)生命尊重與關(guān)愛(ài)生命，是我們職責(zé)，也是我們的發(fā)展動(dòng)力。我們守護(hù)自己與家人，快樂(lè)工作，享受生活;我們珍視生存的世界，崇尚和諧、友善的人際關(guān)系;熱愛(ài)優(yōu)美、多彩的人居環(huán)境。