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GLRX2 Human
英文名稱:GLRX2 Human總訪問:229
國產(chǎn)/進口:進口半年訪問:2
產(chǎn)地/品牌:prospec產(chǎn)品類別:細胞生物學(xué)試劑
規(guī)       格:ENZ-466 最后更新:2024-12-5
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Catalogue Number ENZ-466
Synonyms Thioltransferase, Glutathione-dependent oxidoreductase 2, TTR, TTR1, GLRX2, GRX2, GRX-2, GLRX-2, Glutaredoxin 2.
Introduction GLRX2 is a multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. Glutaredoxins are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions.
Description Glutaredoxin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 154 amino acids (20-164 a.a.) and having a molecular mass of 17 kDa. The GRX2 is fused to 8 amino acid His tag at C-Terminus.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear colorless solution.
Formulation Glutaredoxin-2 solution contains 20mM Tris-HCl pH-8 & 0.1mM PMSF and 10% glycerol.
Stability 1 week at 2-10°C. For long term store at -20 to -80°C.
Purity Purity of GRX2 is greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence MSAGWLDRAA GAAGAAAAAA SGMESNTSSS LENLATAPVN QIQETISDNC VVIFSKTSCS YCTMAKKLFH DMNVNYKVVE LDLLEYGNQF QDALYKMTGE RTVPRIFVNG TFIGGATDTH RLHKEGKLLP LVHQCYLKKS KRKEFQLEHH HHHH.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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