综合图区亚洲网友自拍|亚洲黄色网络|成人无码网WWW在线观看,日本高清视频色视频kk266,激情综合五月天,欧美一区日韩一区中文字幕页

English | 中文版 | 手機版 企業(yè)登錄 | 個人登錄 | 郵件訂閱
當(dāng)前位置 > 產(chǎn)品目錄 > 試劑 > 細(xì)胞生物學(xué)試劑 > PEDF Human
PEDF Human
英文名稱:PEDF Human總訪問:383
國產(chǎn)/進(jìn)口:進(jìn)口半年訪問:2
產(chǎn)地/品牌:prospec產(chǎn)品類別:細(xì)胞生物學(xué)試劑
規(guī)       格:CYT-580 最后更新:2024-12-5
貨       號:
CAS   號:
參考報價:詢價
立即詢價 電話咨詢
[發(fā)表評論] [本類其他產(chǎn)品] [本類其他供應(yīng)商] [收藏]
銷售商: 北京啟維益成科技有限公司 查看該公司所有產(chǎn)品 >>
  • 產(chǎn)品介紹
  • 公司簡介
Catalogue Number CYT-580
Synonyms Pigment epithelium-derived factor,PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35.
Introduction PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. PEDF is a 50,000 dalton glycoprotein created and secreted in many tissues all the way through the body. A key component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. Additionally, PEDF is capable to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The neuro-protective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins. The recognition of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. To date, PEDF-R is the only signaling receptor known to be used by a serpin family member. The unique range of PEDF activities associate it as a potential therapeutic agent for the treatment of vasculature related neurodegenerative diseases such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR). PEDF in addition has the potential to be functional in the treatment of various angiogenesis-related diseases including a number of cancers.
Description PEDF Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 400 amino acids and having a molecular mass of 44.5 kDa.
The Human PEDF is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation The sterile filtered concentrated (1mg/ml) protein solution was lyophilized with 20mM sodium phosphate buffer & 150mM NaCl pH-7.4.
Solubility Add deionized water to a working concentration of 0.5mg/ml and let the lyophilized pellet dissolve completely.
Stability Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/ thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time.
Purity Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence MQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVR
SSMSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHGTYK
ELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLD
LQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTS
LEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPL
KVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLLSYEGEVTKSLQEMKL
QSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPL
DYHLNQPFIFVLRDTDTGALLFIGKILDPRGP.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
>
bio-equip.com
售后服務(wù)
相關(guān)視頻
資料下載
快速詢價登錄注冊在線詢價 (請留下您的聯(lián)系方式,以便供應(yīng)商聯(lián)系您)
* 姓  名:
* 地  區(qū):
* 單  位:
職  位:
* 手機/電話:
* E-mail:
請寄產(chǎn)品資料:
需要 不需要
請報價格:
需要報價 不需要報價
留  言:
驗證碼:
換一張
發(fā)表評論在線評論(0條)
手機版:PEDF Human
搜索本類產(chǎn)品

更多瀏覽該公司同類產(chǎn)品
您最近瀏覽過的產(chǎn)品
Copyright(C) 1998-2025 生物器材網(wǎng) 電話:021-64166852;13621656896 E-mail:info@bio-equip.com
立即詢價