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                                                              CSNK2B Human, Active
                                                              英文名稱:CSNK2B Human, Active總訪問:262
                                                              國產(chǎn)/進(jìn)口:進(jìn)口半年訪問:1
                                                              產(chǎn)地/品牌:prospec產(chǎn)品類別:細(xì)胞生物學(xué)試劑
                                                              規(guī)       格:PKA-209 最后更新:2024-12-5
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                                                              Catalogue Number PKA-209
                                                              Synonyms Casein kinase II subunit beta, CK II beta, Phosvitin, G5a, CK2B, CK2N, CSK2B, MGC138222, MGC138224.
                                                              Introduction The Casein kinase 2 (EC2.7.11.1) is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes.
                                                              Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2.
                                                              Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.
                                                              Description Casein Kinase 2 beta Human Recombinant is a non-glycosylated polypeptide having a molecular mass of 24.9 kDa.
                                                              Casein Kinase 2 is purified by proprietary chromatographic techniques.
                                                              Source Escherichia Coli.
                                                              Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
                                                              Formulation CSNK2B lyophilized from 25mM Tris-HCl, 500mM NaCl, 1mM DTT, 1mM EDTA, protease inhibitor cocktail, pH 8.5.
                                                              Solubility Solubilize in distilled H2O or 50% glycerol.
                                                              Stability Lyophilized CSNK2B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CSNK2B should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
                                                              Please avoid freeze-thaw cycles.
                                                              Unit definition 1U = 1µmol/min at 37 degree C) using the synthetic peptide RRRDDDSDDD.
                                                              Purity Greater than 95% as determined by SDS-PAGE.
                                                              Biological Activity Specific activity > 1U/mg.
                                                              Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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