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application information | ||
recommended dilution | needs to be determined for each application | |
expected | apparent MW | ||
confirmed reactivity | Recognizes markers of oxidative damage to DNA (8-hydroxy-2’-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine) | |
predicted reactivity | ||
not reactive in | no confirmed exceptions from predicted reactivity known in the moment | |
additional information | protocol for immunostaining using this antibody can be found here | |
selected references | Pilger & Rudiger (2006). 8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures. Int Arch Occup Environ Health. 1: 1-15. Kowluru et al. (2006). Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy.Invest Ophthalmol Vis Sci 4: 1594-9. Kim et al. (2003). Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells. Carcinogenesis 2: 235-241. |