product information

background
 

Human Kallikrein 5 (KLK5) is a serine protease produced in its inactive form. It is found in catalytically active form in stratum corneum. It has been reported to degrade desmosomes/corneodesmosomes, suggesting that it is involved in desquamtion. Egelrud et al. (2005) hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. J Invest Dermatol, 124(1):198-203.Alternative names: stratum corneum tryptic enzyme,  Kallikrein-like protein 2, KLK-L2

immunogen
 

KLH-conjugated mix of two synthetic peptides: one chosen from C-terminal and the other one from midregion of human KLK5 Q9Y337

antibody format
 

rabbit;

polyclonal;

serum;

lyophilized

quantity
 

200 µl

- for reconstitution add 200 µl of sterile water

storage
 

store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

tested applications
 

Western blot (WB)

related products
 

AS06 101 | anti-Kallikrein 14

AS06 103 | anti-pro-Kallikrein 5

additional information
 

to be added when available

application information

recommended dilution
 

1: 1000 with standard ECL (WB)

expected | apparent MW
 

32 | 37 kDa

confirmed reactivity
 

human

predicted reactivity
 

human

not reactive in
 

no confirmed exceptions from predicted reactivity known in the moment

additional information
 

antibody is recognizing denatured active Kallikrein 5

selected references
 

to be added when available

Western blot experiment example

 

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