中文名稱 磷酸化絲裂原活化蛋白激酶激酶1重組兔單克隆抗體 

別    名 MEK1 (S298); MEK1 (Dphospho Ser298); MEK1 (phospho S298); p-MEK1 (Ser298); p-MEK1 (S298); ual specificity mitogen activated protein kinase kinase 1; ERK activator kinase 1; MAP kinase kinase 1; MAP kinase/Erk kinase 1; MAP/Erk kinase 1; Map2K1; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; MEKK1; Mitogen activated protein kinase kinase 1; MKK 1; MKK1; PRKMK 1; PRKMK1;Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1); Protein kinase mitogen activated kinase 1; Protein kinase mitogen activated, kinase 1; MP2K1_HUMAN.    

產(chǎn)品類型 磷酸化抗體  

研究領(lǐng)域 腫瘤  細胞生物  免疫學  神經(jīng)生物學  信號轉(zhuǎn)導  細胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶   

抗體來源 Rabbit 

克隆類型 Monoclonal 

克 隆 號 20B10 

交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, ) 

產(chǎn)品應用 WB=1:1000-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 （石蠟切片需做抗原修復）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user. 

分 子 量 43kDa 

細胞定位 細胞核 細胞漿  

性    狀 Liquid 

濃    度 1mg/ml 

免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human MAPKK1 around the phosphorylation site of Ser298:PL(p-S)SY  

亞    型 IgG 

純化方法 affinity purified by Protein A 

儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 

保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 

PubMed PubMed 

產(chǎn)品介紹 The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

 

Function

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