中文名稱 神經(jīng)纖毛蛋白1重組兔單克隆抗體 

別    名 Neuropilin-1; NRP-1; Neuropilin1; BDCA4; CD 304; CD304; DKFZp686A03134; DKFZp781F1414; NEL like protein 1; Nel related protein 1; Neuropilin1; Neuropilin 1; Neuropilin1 transmembrane receptor; NP1; NRP 1; NRP; NRP1; OTTHUMP00000020818; OTTHUMP00000020820; OTTHUMP00000020821; Vascular endothelial cell growth factor 165 receptor; VEGF165R; A5 protein; BLOOD DENDRITIC CELL ANTIGEN 4; NRP1_HUMAN.   

研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  生長(zhǎng)因子和激素  細(xì)胞膜受體  內(nèi)皮細(xì)胞   

抗體來(lái)源 Rabbit 

克隆類型 Monoclonal 

克 隆 號(hào) 49H9 

交叉反應(yīng) (predicted: Human, Mouse, Rat, ) 

產(chǎn)品應(yīng)用 WB=1:1000-5000 IP=1:20-100 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 （石蠟切片需做抗原修復(fù)）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user. 

分 子 量 103kDa 

細(xì)胞定位 細(xì)胞膜 分泌型蛋白  

性    狀 Liquid 

濃    度 1mg/ml 

免 疫 原 KLH conjugated synthetic peptide derived from human Neuropilin-1:  

亞    型 IgG 

純化方法 affinity purified by Protein A 

儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 

保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 

PubMed PubMed 

產(chǎn)品介紹 This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

 

Function:

The membrane-bound isoform 1 is a receptor involved in the development of t

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