產品名稱：類胰蛋白酶α/β1 多克隆抗體-TRYB1 Polyclonal Antibody

產品貨號：ABP60777

產品規(guī)格：30ul/100ul/200ul

應用類型：WB#ELISA

保存建議：類胰蛋白酶α/β1 多克隆抗體-TRYB1 Polyclonal Antibody自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為最大限度的避免損失，請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復凍融。

背景資料：Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

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關鍵詞：TRYB1 Polyclonal Antibody，類胰蛋白酶α/β1 多克隆抗體，TRYB1