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Abeta (1-42) | Amyloid-beta peptide 1-42
英文名稱:Abeta (1-42) | Amyloid-beta peptide 1-42總訪問:836
國產(chǎn)/進(jìn)口:進(jìn)口半年訪問:1
產(chǎn)地/品牌:agrisera產(chǎn)品類別:抗體
規(guī)       格:AS08357 最后更新:2024-12-5
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product information
background

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067

immunogen

synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A

antibody format

rabbit;

polyclonal;

serum;

lyophilized

quantity

100 µl

- for reconstitution add 100 µl of sterile water

storage

store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

tested applications

Western blot (WB), Dot Blot (Dot), ELISA (ELISA)

related products

Alzheimer | available antibodies for Alzheimer's disease

additional information

to be added when available

application information
recommended dilution

1:1000 (WB), 1:1000 (Dot), 1:3000 (ELISA)

expected | apparent MW

4.5 kDa

confirmed reactivity

human

predicted reactivity

bovine, chicken, dog, porcine, rabbit

not reactive in

no confirmed exceptions from predicted reactivity known in the moment

additional information

the antibody can detect Abeta(1-42), Abeta(1-28) Abeta(1-20) and Abeta(1-17)

selected references

to be added when available


Dot blot and Western analysis

•Membrane: Nitrocellulose
•Blocking buffer: 5% dry milk in PBS, 0.15% Tween 20
•Antibody dilution : 1:1000
•Secondary antibody: anti-rabbit (HRP)
•Detection: Enhanced Chemoluminescence (pico) 10s

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